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The T-Charge platform preserves T cell stemness, the ability to self-renew and mature, which results in a product containing greater proliferative potential and fewer exhausted T cells 3 ,4. For the 11 patients with multiple myeloma who received the two highest doses of PHE885, the best overall response was 100% 2. Notably, initial efficacy data show a complete response rate of 73% (95% CI: 44.9, 92.2) at month three for the 15 patients with diffuse large B-cell lymphoma (DLBCL) who received dose level two of YTB323 1. At the 63rd American Society of Hematology Annual Meeting & Exposition (ASH) 2021, Novartis will present early clinical data from ongoing Phase I clinical trials with YTB323 (anti-CD19) and PHE885 (anti-BCMA), the first Novartis CAR-T cell therapies developed using this platform.
With the implementation of important process efficiencies, the T-Charge platform will be rapid, compared with traditional CAR-T, and reliable, through simplified processes and streamlined quality control 1-4īasel, DecemNovartis today announced the introduction of T-Charge™, the company’s next-generation CAR-T platform that will serve as the foundation for various new investigational CAR-T cell therapies in the Novartis pipeline. Novartis continues to accelerate development of the T-Charge platform, which preserves T cell stemness, an important characteristic closely tied to its therapeutic potential, and implements important process efficiencies 3 ,4. Initial efficacy results include 73% complete response rate at month three with dose level two in the YTB323 study in DLBCL and 100% best overall response in the PHE885 study in multiple myeloma 1,2. Early data from first-in-human dose-escalation trials with YTB323 and PHE885 show promising results that support ongoing research and development with the hope of improving upon existing CAR-T therapies 1,2. T-Charge, a next-generation platform that aims to revolutionize CAR-T cell therapy, will serve as foundation for various investigational CAR-T therapies. RAPIDCART 3 UPGRADE
Additional pricing, as well as upgrade pricing, can be found here.
RAPIDCART 3 LICENSE
The price quoted reflects the price for a new license for the Starter edition.
RAPIDCART 3 PRO
RapidCart Pro comes in Starter and Advanced editions. We partnered with some great developers to create beautiful themes with extra functionalities designed for RapidCart Pro.
Themes for RapidCart Pro - RapidCart Pro works with most official and 3rd-party themes for RapidWeaver. Stacks of Features - RapidCart Pro is designed to work with Yourhead Stacks to further customize your store layout. RAPIDCART 3 UPDATE
Endless Configuration Options - Easily customize your store layout, choose your preferred payment gateways, set the price point at which free shipping applies: configuration options are really endless, and each minor update will bring new ones!.
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Accept payments using Stripe, PayPal, and Mollie, or choose to handle offline payments such as cash-on-delivery or wire transfer. Multiple Payment Gateways - RapidCart Pro supports multiple payment gateways, each with its own commissions settings.
RapidCart Pro has the enterprise-class features and the flexibility you need to create an e-commerce solution tailored to your unique needs.
Sell Like a Pro - RapidCart Pro makes it easy to build and manage a powerful and fully customizable online store with RapidWeaver. RapidCart Pro is a powerful RapidWeaver plugin for running an e-commerce store.
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